When a Ledger USB connection is not recognized, treat it as an environment check before drawing conclusions. Move through cable, port, system permission, Ledger Wallet page state, and device screen in order. Change one condition at a time so the result is readable.

Check cable and port as the physical layer
Use a USB cable that supports data, try one direct computer port, and avoid changing several adapters at once. For the baseline desktop sequence, compare with connecting Ledger to a computer.
Review operating-system permission
A system prompt or driver state can affect recognition. On Windows, use the Windows driver and port checklist. On Mac, compare with the Mac permission and USB path guide.
Read Ledger Wallet page state
Open Ledger Wallet and check whether the page is waiting for device unlock, an app to be opened, or a permission change. If the app cannot open the device, use the Ledger Wallet device-opening checklist before repeating the same USB step.
Confirm the device screen before changing more
The device should be unlocked and showing a screen that matches the task. If a version or device-app prompt appears, record it and handle it separately. This prevents a USB check from turning into a broad setup reset.