If Ledger does not connect to a PC, check four layers first: app entry, USB path, operating-system permission, and device screen. Do not treat the first failed connection as a final device conclusion. A clear four-layer check makes the next step easier to choose.

Layer one: app entry
Confirm that Ledger Wallet opens from a stable entry and is not part of an incomplete install or update flow. If the app entry is uncertain, return to Official App Download and Installation Guide before continuing.
Layer two: USB path
Try a data-capable cable and a direct port before changing other settings. Cable and port checks should be recorded separately so the result can be compared later. For broader connection context, read Ledger Connection Troubleshooting.
Layer three: system permission
Operating systems may need permission or driver context before the app can open the device. Change only one permission or port condition at a time, then record the visible change.
Layer four: device screen
Read the Ledger device screen after each attempt. If the screen is waiting for a different task, return to the setup or app entry step rather than clicking through repeated prompts.
The local note should include PC system, app entry, cable used, port used, permission state, and device-screen state. Do not include private setup material.
If the connection later works, the note will show which layer changed. If it still does not work, the next check can begin from facts instead of repeating every condition.